Church of PeptidesSearch
One key, two keys, three

GLP-1, GIP and Glucagon Medicines Explained

GLP-1, GIP, and glucagon are related metabolic signals. Modern medicines may target one pathway or deliberately combine activity across two or three receptors.

Plain-language guide

The signals

GLP-1An incretin signal that helped establish a modern therapeutic class.GIPGlucose-dependent insulinotropic polypeptide; its receptor is one of the two targets of tirzepatide. FDA prescribing information.GlucagonA peptide hormone with approved products and a separate role in multi-receptor research.
Plain-language guide

Medicine examples

LiraglutideGLP-1 receptor agonist.SemaglutideGLP-1 receptor agonist with product-specific labels.TirzepatideDual GIP and GLP-1 receptor agonist.RetatrutideInvestigational GIP, GLP-1, and glucagon receptor agonist.SurvodutideInvestigational GLP-1 and glucagon receptor agonist.
Plain-language guide

Read labels carefully

Sharing a pathway does not make medicines interchangeable. Approval, indication, formulation, trial population, benefits, and risks must be evaluated product by product.

Sacred footnotes

Primary reference points

  1. FDA · Drugs@FDA
  2. ClinicalTrials.gov

Editorial review: Church of Peptides Editorial Desk · Independent clinical review: none to date.

Educational information only. No diagnosis, dosing, prescribing, purchasing, or individualized treatment advice.