The Book of Trials
Follow the research questions. Keep the evidence in view.
Each journey has six short chapters. Read the story, then open the study notes when you want the detail.

Investigational · Not FDA-approved
Retatrutide
Why try three signals in one medicine?
Start the story →
Approved products · Uses differ by product
Semaglutide
How do you make a short-lived signal last?
Start the story →
Approved products · Uses differ by product
Tirzepatide
Why give one molecule two receptor targets?
Start the story →
Investigational · Not FDA-approved
Petrelintide
Before asking whether it works, can the molecule stay stable?
Start the story →
Investigational · GLP-1/glucagon dual agonist
Survodutide
Can one molecule activate two different receptors?
Start the story →
Investigational combination · Human trial evidence
CagriSema
Does combining the ingredients improve the same outcomes equally?
Start the story →
Human trial evidence · Approved product with defined indications
Liraglutide
What did the weight-management trial actually measure?
Start the story →Subject One is fictional. His changing role represents separate laboratory, animal and human studies—not one person receiving every treatment.