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The Book of Trials

Follow the research questions. Keep the evidence in view.

Each journey has six short chapters. Read the story, then open the study notes when you want the detail.

The fictional Retatrutide character
Investigational · Not FDA-approved

Retatrutide

Why try three signals in one medicine?

Start the story →
The fictional Semaglutide character
Approved products · Uses differ by product

Semaglutide

How do you make a short-lived signal last?

Start the story →
The fictional Tirzepatide character
Approved products · Uses differ by product

Tirzepatide

Why give one molecule two receptor targets?

Start the story →
The fictional Petrelintide character
Investigational · Not FDA-approved

Petrelintide

Before asking whether it works, can the molecule stay stable?

Start the story →
The fictional Survodutide character
Investigational · GLP-1/glucagon dual agonist

Survodutide

Can one molecule activate two different receptors?

Start the story →
Patient One, the fictional guide to CagriSema’s clinical evidence
Investigational combination · Human trial evidence

CagriSema

Does combining the ingredients improve the same outcomes equally?

Start the story →
Patient One, fictional guide to liraglutide research
Human trial evidence · Approved product with defined indications

Liraglutide

What did the weight-management trial actually measure?

Start the story →

Subject One is fictional. His changing role represents separate laboratory, animal and human studies—not one person receiving every treatment.

About the stories and sources